POLYNUCLEOTUIDES
What are Polynucleotides?
Polynucleotides use your skin's own biology to repair, regenerate, and renew. Ideal for laxity, fine lines, dark circles, and sun damage, this innovative injectable treatment delivers gradual, natural-looking improvement from the inside out. Book at Hook Clinic today.
At a glance
Technology
Polynucleotides (PN/PDRN) are injectable treatments derived from highly purified salmon DNA fragments. Once in the skin, they activate the body's own cellular repair mechanisms — stimulating fibroblasts to produce collagen, elastin, and hyaluronic acid, while reducing inflammation and promoting tissue healing at a fundamental level.
Results
Progressive improvement in skin quality, firmness, hydration, and tone. Results are gradual and biological rather than immediate — clients typically notice the most significant change after completing their course, with continued improvement over the following months.
sessions
A course of 3–4 sessions spaced 2–4 weeks apart is recommended. Results are cumulative and continue to develop for several weeks after each treatment.
Process
A topical numbing cream may be applied before treatment, particularly for sensitive areas such as under the eyes. Polynucleotides are injected via a series of small, shallow injections across the treatment area. Sessions take approximately 30–45 minutes.
works for
Skin laxity, fine lines, crepey or thinning skin, under-eye hollowness and dark circles, post-acne scarring, and heavily sun-damaged skin. An excellent option for clients seeking genuine biological skin repair and regeneration.
Downtime
Mild redness, small injection-point marks, and occasional light swelling settle within 24 hours. Some bruising is possible, particularly in the under-eye area.
Why choose Us?
Holistic Approach
Comprehensive skin consultations combined with ongoing skincare guidance to enhance and maintain your long-term results.
medical expertise
Treatments led and directed by experienced medical professionals with specialized training.
Advanced technology
We use the best technology, ensuring precise, safe results with minimal downtime.
WHAT IT TREATS
Under eye crepiness
Lines around mouth
Neck, particularly ‘necklace lines’
Fine lines
FAQs
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We use numbing cream to help make this more comfortable but patients do find this treatment uncomfortable and we would generally not recommend polynucletides as your first experience of injectable treatments.
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We carry out a full consultation before recommending treatment. While many skin types are suitable, we carefully assess your skin tone and history to ensure safe, effective results.
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Little bee sting-like blebs are commong after treatment and can last anywhere from a couple of hours to 72 hours in some people.
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Most clients achieve best results with 3 spaced 2-4 weeks apart. We'll recommend the right number during your consultation based on your specific concerns.
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With proper skincare and sun protection, results can last 8-12 months. We provide ongoing guidance to help you maintain your results long-term. Yearly maintenance sessions advised.
Not sure what treatments are right for you?
Try our Comprehensive Skin Consultation
This service is recommended for all new clients. We'll discuss your skin concerns, goals, and budget to create a personalised 12-month treatment plan.
What to bring: Your current skincare products (or photos of ingredients lists)
Bonus: Many treatments can be performed during your consultation appointment.
Pricing: €75 Fully redeemable against products or services booked on the same day